Note: This unit version is currently being edited and is subject to change!

BMET3660: Biomanufacturing (2019 - Semester 1)

Download UoS Outline

Unit: BMET3660: Biomanufacturing (6 CP)
Mode: Normal-Day
On Offer: Yes
Level: Senior
Faculty/School: School of Aerospace, Mechanical & Mechatronic Engineering
Unit Coordinator/s: Prof Suaning, Gregg
Session options: Semester 1
Versions for this Unit:
Campus: Camperdown/Darlington
Pre-Requisites: MECH2400 OR ENGG1960 OR AMME1960 OR AMME1961 OR ENGG1800 OR MECH1560.
Prohibitions: MECH3660 OR AMME3660.
Brief Handbook Description: The unit aims to teach the fundamentals of biomedical manufacturing processes, including traditional and advanced manufacturing technologies.

This unit aims to develop the following attributes: to understand the fundamental principles of biomedical manufacturing approaches; to gain the ability to understand and select appropriate manufacturing processes and systems for biomedical applications; to develop ability to create innovative new manufacturing technologies for medical bionics and other applications in biomedical engineering; to develop ability to invent new manufacturing systems suitable for biomedical engineering implementation.

At the end of this unit students will have a good understanding of the following: merits and advantages of individual manufacturing processes and systems used in the fabrication of medical devices and products that support human health and well-being; principles of developing new technologies for biomedical engineering applications; comprehensive applications and strategic selection of manufacturing processes and systems within the regulatory landscape of biomedical manufacturing.

Unit content will include:

Materials Processing: An introduction into the use of joining, moulding, and other manufacturing processes.

Rapid Prototyping: An introduction into the most current prototyping methods currently in use.

Manufacturing Processes: Common processes and their science (machining, moulding, sintering, materials processing, joining processes) and their relative merits and limitations.
Assumed Knowledge: None.
Lecturer/s: Prof Suaning, Gregg
Tutor/s: Apurv Yadav - Laboratory Demonstrator

Fred Westling - Laboratory Demonstrator

John Gardenier - Laboratory Demonstrator

Josh Riley - Laboratory Demonstrator

Mark Lagana - Laboratory Demonstrator

Xing (Edgar) Wang - Laboratory Demonstrator

Jasper Brown - Laboratory Demonstrator

Jacob Mackay - Laboratory Demonstrator
Timetable: BMET3660 Timetable
Time Commitment:
# Activity Name Hours per Week Sessions per Week Weeks per Semester
1 Lecture 2.00 2 13
2 Various Topics per timetable 2.00 1 7
3 Independent Study 5.00 1 13

Attributes listed here represent the key course goals (see Course Map tab) designated for this unit. The list below describes how these attributes are developed through practice in the unit. See Learning Outcomes and Assessment tabs for details of how these attributes are assessed.

Attribute Development Method Attribute Developed
Understanding of the common manufacturing processes and essential skills in planning the manufacture of a product intended for use in the provision of healthcare. (2) Engineering/ IT Specialisation (Level 3)
Design of manufacturing processes in the fabrication of medical devices. (4) Design (Level 3)
Participation in team assignments (7) Project and Team Skills (Level 3)

For explanation of attributes and levels see Engineering & IT Graduate Outcomes Table 2018.

Learning outcomes are the key abilities and knowledge that will be assessed in this unit. They are listed according to the course goal supported by each. See Assessment Tab for details how each outcome is assessed.

(7) Project and Team Skills (Level 3)
1. Ability to contribute to effective team processes.
(4) Design (Level 3)
2. Ability to determine functional requirements of a product in terms of its application and suitability, etc.
3. Ability to determine the basic manufacturing considerations necessary to realise the function, including the selection of materials and the manufacturing method, taking into account the strength, reliability and intended use in the provision of healthcare.
4. Ability to discuss the merits and disadvantages of individual manufacturing methods in the context of suitability of use in biomedical engineering of devices.
5. Ability to discuss the major problems in the current manufacturing practice and your suggestions to overcome or improve them. Students are encouraged to do an investigation which may include a visit to a manufacturer or laboratory within the university that carries out manufacturing operations.
(2) Engineering/ IT Specialisation (Level 3)
6. Understanding the fundamental principles of manufacturing technologies for biomedical engineering.
7. Familiarity with quality management principles in biomedical manufacturing.
Assessment Methods:
# Name Group Weight Due Week Outcomes
1 Quiz 1: Quality, Processes,Design* No 20.00 Week 4 2, 3, 4, 6, 7,
2 Assignment 1: Quality Management/Biomanufacture* Yes 15.00 Week 6 1, 2, 3, 6, 7,
3 Quiz 2 – Automation* No 20.00 Week 9 1, 2, 3, 4, 5, 6, 7,
4 Assignment 2 - Automation* Yes 15.00 Week 10 1, 2, 3, 6, 7,
5 Laboratory Assignment 1 Yes 5.00 Multiple Weeks 1, 3, 4, 5,
6 Laboratory Assignment 2 Yes 5.00 Multiple Weeks 1, 3, 4, 5,
7 Final Examination No 20.00 Exam Period 2, 3, 4, 5, 6, 7,
Assessment Description: * indicates an assessment task which must be repeated if a student misses it due to special consideration.

All Assignments will be submitted online unless otherwise advised. All written material is subject to scanning for appropriate referencing using, for example, Turnitin.

Quizzes:

The unit has two quizzes that cover approximately one-third of the semester each, with the final examination containing one third (approximately)**IN ADDITION TO ANY MATERIAL COVERED THROUGHOUT THE UNIT**. Quizzes and exams may cover material that includes assignments, laboratories, and lecture content.

Laboratories:

There are multiple laboratories scheduled during the semester. All of these are compulsory and are to be attended at the scheduled time according to each students individual timetable.
Assessment Feedback: Assessment feedback is by way of written comments on a marking sheet.

General feedback will also be provided during the lecture and individual feedback as needed can be provided in scheduled meetings upon request.
Grading:
Grade Type Description
Standards Based Assessment Final grades in this unit are awarded at levels of HD for High Distinction, DI (previously D) for Distinction, CR for Credit, PS (previously P) for Pass and FA (previously F) for Fail as defined by University of Sydney Assessment Policy. Details of the Assessment Policy are available on the Policies website at http://sydney.edu.au/policies . Standards for grades in individual assessment tasks and the summative method for obtaining a final mark in the unit will be set out in a marking guide supplied by the unit coordinator.
Policies & Procedures: See the policies page of the faculty website at http://sydney.edu.au/engineering/student-policies/ for information regarding university policies and local provisions and procedures within the Faculty of Engineering and Information Technologies.
Prescribed Text/s: Note: Students are expected to have a personal copy of all books listed.
  • Biomanufacturing
Recommended Reference/s: Note: References are provided for guidance purposes only. Students are advised to consult these books in the university library. Purchase is not required.

Note that the "Weeks" referred to in this Schedule are those of the official university semester calendar https://web.timetable.usyd.edu.au/calendar.jsp

Week Description
Week 1 Lecture: Unit Introduction / Manufacturing Processes
Lecture: Quality Management Systems (QMS) and ISO13485
Week 2 Lecture: What could possibly go wrong? Case Studies in QMS
Lecture: A Philosophical Approach to Medical Implant Design
Week 3 Lecture: Bugs and the biomedical industry
Lecture: Pyrogens, Pathogens and Particles
Week 4 Lecture: Sintering and its Role in Medical Device Manufacture
Assessment Due: Quiz 1: Quality, Processes,Design*
Week 5 Lecture: Manufacturing Automation: Intro to Automation and Testing
Lecture: Manufacturing Automation: Automated Inspection Systems
Week 6 Lecture: Manufacturing Automation: VBAI – Finding Features
Lecture: Manufacturing Automation: VBAI – Measuring features and Character Recognition
Assessment Due: Assignment 1: Quality Management/Biomanufacture*
Week 7 Lecture: Manufacturing Automation: VBAI – Image Analysis and Intro to Motion Systems
Lecture: Manufacturing Automation: Data Acquisition & LabVIEW
Week 8 Lecture: Manufacturing Automation: Analogue Sampling & LabVIEW
Lecture: Manufacturing Automation: Data Processing with LabVIEW
Week 9 Lecture: Failure Modes and Effects Analysis (FMEA)
Assessment Due: Quiz 2 – Automation*
Week 10 Lecture: Joining Processes in Medical Device Manufacture
Lecture: Moulding Processes in Medical Device Manufacture
Assessment Due: Assignment 2 - Automation*
Week 11 Lecture: Fabrication Methods in Medical Devices
Lecture: Fabrication Methods in Medical Devices
Week 12 Lecture: Materials Processing in Medical Device Manufacture
Lecture: Nano Manufacturing
Week 13 Lecture: Microfluidics
Lecture: Ethics Debate
Exam Period Assessment Due: Final Examination

Course Relations

The following is a list of courses which have added this Unit to their structure.

Course Year(s) Offered
Biomedical Mid-Year 2019, 2020, 2018
Biomedical/ Project Management 2019, 2020
Biomedical 2016, 2017, 2018, 2019, 2020
Biomedical / Arts 2019, 2020
Biomedical / Commerce 2019, 2020
Biomedical /Science 2019, 2020
Biomedical/Science (Health) 2019, 2020
Biomedical / Law 2019, 2020
Biomedical/Science (Medical Science Stream) 2019, 2020

Course Goals

This unit contributes to the achievement of the following course goals:

Attribute Practiced Assessed
(7) Project and Team Skills (Level 3) Yes 11%
(8) Professional Effectiveness and Ethical Conduct (Level 2) No 0%
(5) Interdisciplinary, Inclusiveness, Influence (Level 3) No 0%
(4) Design (Level 3) Yes 53%
(3) Problem Solving and Inventiveness (Level 3) No 0%
(2) Engineering/ IT Specialisation (Level 3) Yes 36%

These goals are selected from Engineering & IT Graduate Outcomes Table 2018 which defines overall goals for courses where this unit is primarily offered. See Engineering & IT Graduate Outcomes Table 2018 for details of the attributes and levels to be developed in the course as a whole. Percentage figures alongside each course goal provide a rough indication of their relative weighting in assessment for this unit. Note that not all goals are necessarily part of assessment. Some may be more about practice activity. See Learning outcomes for details of what is assessed in relation to each goal and Assessment for details of how the outcome is assessed. See Attributes for details of practice provided for each goal.